Budesonide | 2773

Budesonide is a glucocorticoid steroid that activates the glucorcorticoid receptor (EC₅₀ = 12.4 nM). Like other glucocorticoids, budesonide reduces inflammation and has utility in inflammatory diseases, like asthma and inflammatory bowel disease. Reverses DNA hypomethylation and modulates expression of cancer related genes.

Budesonide is a glucocorticoid steroid that activates the glucorcorticoid receptor (EC₅₀ = 12.4 nM). Like other glucocorticoids, budesonide reduces inflammation and has utility in inflammatory diseases, like asthma and inflammatory bowel disease. Reverses DNA hypomethylation and modulates expression of cancer related genes.

2773 | Budesonide DataSheet

Alternate Name/Synonyms: 16α,​​17-​​[butylidenebis(oxy)​]​-​​11β,​​21-​​dihydroxy-​pregna-​​1,​​4-​​diene-​​3,​​20-​​dione; Pulmicort; Entocort

Appearance: White solid

Formulation: N/A

CAS Number: 51333-22-3

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₅H₃₄O₆

Molecular Weight: 430.53

Cell-Permeable?: Y

Purity: ≥95%

Solubilities: DMSO (~40 mg/ml) or EtOH (~20 mg/ml)

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A glucocorticoid receptor activator

MDL Number: MFCD00083259

PubChem CID: 5281004

SMILES: CCCC1OC2CC3C4CCC5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C

InChi: InChI=1S/C25H34O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28)12-24(17,3)25(20,31-21)19(29)13-26/h8-10,16-18,20-22,26,28H,4-7,11-13H2,1-3H3/t16-,17-,18-,20+,21?,22+,23-,24-,25+/m0/s1

InChi Key: VOVIALXJUBGFJZ-KWVAZRHASA-N