CA19-9 Antibody (Clone# 121SLE), Carrier-Free | A2227

CA19-9, a carbohydrate epitope expressed on a high MW (400 kDa) mucin glycoprotein, is a sialyl Lewisa structure that is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in the ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict the recurrence of disease before radiographic or clinical findings. This BSA and Azide-free monoclonal antibody are excellent for staining of formalin-fixed, paraffin-embedded tissues.

A2227 | CA19-9 Antibody (Clone# 121SLE), Carrier-Free DataSheet

Antibody Target: CA19-9

Target Alternative Name: Pancreatic tumor antigen, Ovarian tumor antigen, Sialyl Lewisa, CA19.9

Tag Line: BSA and Azide-free mouse monoclonal antibody to detect CA19-9 in human samples

Category: Cancer

Host: Mouse

Isotype: IgM, kappa

Species Reactivities: Human

Immunogen Sequence: Precipitin lines obtained after immuno-diffusion using MAb 116-NS-19-9 and mucins isolated from an ovarian cyst of a Lewis A+B- patient

Accession #:

Gene ID:

Appearance: Colorless liquid

Form: Liquid

Concentration: 1 mg/ml

Formulation: In 10 mM PBS

Purification: Protein A/G purification

Application: Immunohistochemistry (IHC)

Positive Control: Human Stomach, Gastric Carcinoma

Application And Usages: IHC 1-2 µg/ml

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: FALSE

Immunocytochemistry Verified: FALSE

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE