26
CA19-9 Antibody (Clone# 121SLE), Carrier-Free | A2227
- SKU:
- 26-A2227-100-GEN
- Availability:
- Usually shipped in 5 working days
Description
CA19-9, a carbohydrate epitope expressed on a high MW (400 kDa) mucin glycoprotein, is a sialyl Lewisa structure that is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in the ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict the recurrence of disease before radiographic or clinical findings. This BSA and Azide-free monoclonal antibody are excellent for staining of formalin-fixed, paraffin-embedded tissues.
A2227 | CA19-9 Antibody (Clone# 121SLE), Carrier-Free DataSheet
Antibody Target: CA19-9
Target Alternative Name: Pancreatic tumor antigen, Ovarian tumor antigen, Sialyl Lewisa, CA19.9
Tag Line: BSA and Azide-free mouse monoclonal antibody to detect CA19-9 in human samples
Category: Cancer
Host: Mouse
Isotype: IgM, kappa
Species Reactivities: Human
Immunogen Sequence: Precipitin lines obtained after immuno-diffusion using MAb 116-NS-19-9 and mucins isolated from an ovarian cyst of a Lewis A+B- patient
Accession #:
Gene ID:
Appearance: Colorless liquid
Form: Liquid
Concentration: 1 mg/ml
Formulation: In 10 mM PBS
Purification: Protein A/G purification
Application: Immunohistochemistry (IHC)
Positive Control: Human Stomach, Gastric Carcinoma
Application And Usages: IHC 1-2 µg/ml
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: FALSE
Immunocytochemistry Verified: FALSE
Immunofluorescence Verified: FALSE
Immunoprecipitation Verified: FALSE
FACS Verified: FALSE
ELISA Verified: FALSE
ChIP Verified: FALSE
Dot Blot Verified: FALSE
Flow Cytometry Verified: FALSE
Additional Information
Size: |
100 ug |
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |