Caspase-1 Substrate YVAD-pNA | 1104

Ready-to-use colorimetric substrate for caspase-1/ICE and related caspases that recognize the amino acid sequence YVAD. Caspase-1 and related caspase activity can be quantified by spectrophotometric detection of free pNA (l= 400 nm) after cleavage from the peptide substrate YVAD-pNA, using a spectrophotometer or multi-well plate reader. The ready-to-use caspase substrate provides an economic alternative for large volume users.

YVAD-pNA is a ready-to-use fluorometric substrate for caspase-1/ICE and related caspases that recognize the amino acid sequence YVAD.

1104 | Caspase-1 Substrate YVAD-pNA DataSheet

Alternate Name/Synonyms: Ac-YVAD-pNA, Caspase-1 Substrate, Colorimetric

Appearance: Liquid

Formulation: DMSO (4 mM)

CAS Number: N/A

Structure Available?: No

Peptide sequence: Ac-Tyr-Val-Ala-Asp-pNA

Salt Form: No

Molecular Formula: C₂₉H₃₆N₅O₁₀

Molecular Weight: 628.6

Cell-Permeable?: No

Purity: >98% by HPLC

Solubilities: N/A

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A caspase-1 substrate

MDL Number: N/A

PubChem CID: 10484117

SMILES: CC(C)C(C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C

InChi: InChI=1S/C29H36N6O10/c1-15(2)25(34-28(42)22(31-17(4)36)13-18-5-11-21(37)12-6-18)29(43)30-16(3)26(40)33-23(14-24(38)39)27(41)32-19-7-9-20(10-8-19)35(44)45/h5-12,15-16,22-23,25,37H,13-14H2,1-4H3,(H,30,43)(H,31,36)(H,32,41)(H,33,40)(H,34,42)(H,38,39)/t16-,22-,23-,25-/m0/s1

InChi Key: YDPNOCSPPGFBPX-XNHCRPTKSA-N