Caspase-6 Antibody| F42752-0.08ML/F42752-0.4ML/R30512

Caspase-6 Antibody| F42752-0.08ML/F42752-0.4ML/R30512 | Gentaur UK, US & Europe Distribution

Background: CASP6 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein could be processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human, Mouse

Predicted Spacies Reactivity: Rat, Bovine

Application: WB, IHC, ELISA

Application Details: Western blot: 1:1000, IHC (Paraffin): 1:10-1:50

Application Note: Titration of the Caspase-6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This Caspase-6 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 235-263 from the human protein was used as the immunogen for this Caspase-6 antibody.

Storage: Aliquot the Caspase-6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A