CD160 Antibody | 7475

CD160 Antibody | 7475 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: CD160 antibody was raised against a 17 amino acid peptide near the center of human CD160.
The immunogen is located within amino acids 50 - 100 of CD160 .

Research Area: Immunology

Tested Application: E, WB, IF

Application: CD160 antibody can be used for detection of CD160 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: CD160 antibody is human and mouse reactive. Multiple isoforms of CD160 are known to exist.

Positive Control 1: Cat. No. 1204 - K562 Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 20 kDa
Observed: 25kDa

Validation: N/A

Isoform: N/A

Purification: CD160 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: CD160 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: CD160 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: CD160 Antibody : NK1, BY55, NK28, CD160 antigen, Natural killer cell receptor BY55

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CD160, also known as BY55, is a lipid-anchored cell membrane glycoprotein that contains one immunoglobulin-like domain (1) . It is expressed in small intestine, spleen and functional NK and T cytotoxic lymphocytes (1, 2) . CD160 exists as a disulfide-linked homomultimer that functions as a receptor for MHC (major histocompatability complex) molecules and is thought to regulate the function of NK cells (2, 3) . Additionally, CD160 interacts with TNFRSF14 and, via this interaction, is able to negatively regulate CD4+ T cell activation, indicating a role in immune system regulation (4) .