Description
CD160 Antibody | 7475 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse
Homology: N/A
Immunogen: CD160 antibody was raised against a 17 amino acid peptide near the center of human CD160.
The immunogen is located within amino acids 50 - 100 of CD160 .
Research Area: Immunology
Tested Application: E, WB, IF
Application: CD160 antibody can be used for detection of CD160 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Specificiy: CD160 antibody is human and mouse reactive. Multiple isoforms of CD160 are known to exist.
Positive Control 1: Cat. No. 1204 - K562 Cell Lysate
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Predicted: 20 kDa
Observed: 25kDa
Validation: N/A
Isoform: N/A
Purification: CD160 Antibody is affinity chromatography purified via peptide column.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: CD160 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Condition: CD160 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Alternate Name: CD160 Antibody : NK1, BY55, NK28, CD160 antigen, Natural killer cell receptor BY55
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: CD160, also known as BY55, is a lipid-anchored cell membrane glycoprotein that contains one immunoglobulin-like domain (1) . It is expressed in small intestine, spleen and functional NK and T cytotoxic lymphocytes (1, 2) . CD160 exists as a disulfide-linked homomultimer that functions as a receptor for MHC (major histocompatability complex) molecules and is thought to regulate the function of NK cells (2, 3) . Additionally, CD160 interacts with TNFRSF14 and, via this interaction, is able to negatively regulate CD4+ T cell activation, indicating a role in immune system regulation (4) .