CD4 Antibody| F40306-0.08ML/F44339-0.4ML/R30015/RQ4976/V2381-20UG

CD4 Antibody| F40306-0.08ML/F44339-0.4ML/R30015/RQ4976/V2381-20UG | Gentaur UK, US & Europe Distribution

Background: This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Format: Purified

Clone: OKT4

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Isotype: Mouse IgG2b, k

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: WB, ELISA

Application Details: Western blot: 1:100-1:250

Application Note: Titration of the OKT4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This OKT4 antibody is available for research use only.

Purity: Purified

Immunogen: This monoclonal OKT4 antibody was produced from a mouse immunized with human peripheral T cells.

Storage: Aliquot the OKT4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A