26
CD40Ligand/TRAP, murine recombinant | 4015
- SKU:
- 26-4015-GEN
- Availability:
- Usually shipped in 5 working days
Description
CD40 Ligand (CD40L/TRAP) is a type II transmembrane glycoprotein belonging to the TNF superfamily of ligands. Natually, CD40L is a membrane-bound protein, but proteolytically cleaved 15-18 kDa soluble forms of CD40L are also fully active. CD40L plays an important role in the proliferation and differentiation of B-cells, and is critical for immunoglobulin (Ig) class switching. Recombinant murine CD40 Ligand is a soluble 18 kDa protein containing 149 amino acid residues comprising the receptor binding TNF-like domain of CDE40L.
4015 | CD40Ligand/TRAP murine recombinant DataSheet
Biomolecule/Target: CD40Ligand/TRAP
Synonyms: CD40-L, Tumor necrosis factor ligand superfamily member 5, TNF-related activation protein, TRAP, T cell antigen Gp39, CD154 antigen, sCD40, IGM, IMD3, HIGM1, T-BAM, TNFSF5, hCD40L.
Alternates names: BMP-12/GDF-7, BMP12/GDF7, BMP 12/GDF 7,
Taglines: A protein primarily expressed on activated T cells and involved in immune functions
NCBI Gene ID #: 151449
NCBI Gene Symbol: BMP12/GDF7
Gene Source: Mouse
Accession #: BAD07014
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: 98%
Assay #2: HPLC
Endotoxin Level: <0.1 ng/g
Activity (Specifications/test method): N/A
Biological activity: The protein is biologically active as determined by its ability to induce alkaline phosphatase production by ADTC5 mouse chondrogenic cells. The ED for this effect is typically 0.2 2.5 µg/ml.
Results: <0.1 µg/ml.
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 27 kDa
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: Sterile filtered and then lyophilized from 10 mM Sodium Phosphate, pH 7.5 + 0.1 M Arginine.
Reconstitution Instructions: Reconstitute to a concentration of 0.1-1.0 mg/ml in HO containing BSA (50 µg BSA per 1 µg of protein). This solution can then be diluted into other aqueous buffers.
Amino acid sequence: N/A