CRAT Antibody (N-term) [APG02760G]

CRAT Antibody (N-term) [APG02760G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This CRAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-96 amino acids from the N-terminal region of human CRAT.

Cellular Localisation: Endoplasmic reticulum. Peroxisome. Mitochondrion inner membrane; Peripheral membrane protein; Matrix side [Isoform 2]: Peroxisome

Molecular Weight: 70858

Clone: Polyclonal

Gene Name: CRAT (HGNC:2342)

Gene ID: 1384

Function: Catalyzes the reversible transfer of acyl groups from carnitine to coenzyme A (CoA) and regulates the acyl-CoA/CoA ratio. Also plays a crucial role in the transport of fatty acids for beta- oxidation (PubMed:15099582, PubMed:29395073) . Responsible for the synthesis of short- and branched-chain acylcarnitines (PubMed:23485643) . Active towards some branched-chain amino acid oxidation pathway (BCAAO) intermediates (PubMed:23485643) . Trans-2- enoyl-CoAs and 2-methylacyl-CoAs are poor substrates (PubMed:23485643) .

Summary: Tissue Location: Mostly in skeletal muscle, less in heart, liver and pancreas, only weakly detectable in brain, placenta, lung and kidney

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P

Dilution: WB--1:1000 IHC-P--1:100~500

Synonyms: Carnitine O-acetyltransferase, Carnitine acetylase, Carnitine acetyltransferase, CAT, CrAT, CRAT, CAT1