LBD
CRAT Antibody (N-term) [APG02760G]
- SKU:
- LBD-APG02760G
- Availability:
- Usually ships in 5 working days
Description
CRAT Antibody (N-term) [APG02760G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This CRAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-96 amino acids from the N-terminal region of human CRAT.
Cellular Localisation: Endoplasmic reticulum. Peroxisome. Mitochondrion inner membrane; Peripheral membrane protein; Matrix side [Isoform 2]: Peroxisome
Molecular Weight: 70858
Clone: Polyclonal
Gene Name: CRAT (HGNC:2342)
Gene ID: 1384
Function: Catalyzes the reversible transfer of acyl groups from carnitine to coenzyme A (CoA) and regulates the acyl-CoA/CoA ratio. Also plays a crucial role in the transport of fatty acids for beta- oxidation (PubMed:15099582, PubMed:29395073) . Responsible for the synthesis of short- and branched-chain acylcarnitines (PubMed:23485643) . Active towards some branched-chain amino acid oxidation pathway (BCAAO) intermediates (PubMed:23485643) . Trans-2- enoyl-CoAs and 2-methylacyl-CoAs are poor substrates (PubMed:23485643) .
Summary: Tissue Location: Mostly in skeletal muscle, less in heart, liver and pancreas, only weakly detectable in brain, placenta, lung and kidney
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P
Dilution: WB--1:1000 IHC-P--1:100~500
Synonyms: Carnitine O-acetyltransferase, Carnitine acetylase, Carnitine acetyltransferase, CAT, CrAT, CRAT, CAT1