Description
DAG1 Antibody | 13-415 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 654-749 of human DAG1 (NP_004384.4) .
Research Area: Cell Cycle, Neuroscience, Signal Transduction
Tested Application: WB, IF
Application: WB: 1:500 - 1:1000
IF: 1:20 - 1:100
Specificiy: N/A
Positive Control 1: HepG2
Positive Control 2: U2OS
Positive Control 3: SW480
Positive Control 4: HeLa
Positive Control 5: mouse skeletal muscle
Positive Control 6: mouse lung
Molecular Weight: Observed: 43kDa/95kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: DAG1, dystroglycan 1 (dystrophin-associated glycoprotein 1) , dystroglycan 1, DAG, beta-dystroglycan, alpha-dystroglycan, AGRNR, A3a, 156DAG, MDDGC7, MDDGC9
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein.