DAG1 Antibody | 13-415

DAG1 Antibody | 13-415 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 654-749 of human DAG1 (NP_004384.4) .

Research Area: Cell Cycle, Neuroscience, Signal Transduction

Tested Application: WB, IF

Application: WB: 1:500 - 1:1000
IF: 1:20 - 1:100

Specificiy: N/A

Positive Control 1: HepG2

Positive Control 2: U2OS

Positive Control 3: SW480

Positive Control 4: HeLa

Positive Control 5: mouse skeletal muscle

Positive Control 6: mouse lung

Molecular Weight: Observed: 43kDa/95kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: DAG1, dystroglycan 1 (dystrophin-associated glycoprotein 1) , dystroglycan 1, DAG, beta-dystroglycan, alpha-dystroglycan, AGRNR, A3a, 156DAG, MDDGC7, MDDGC9

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein.