DDR2, Active | 7760

DDR2 is a member of a novel subclass of RTKs containing a distinct extracellular region encompassing a factor VIII-like domain (1) and is thought to be involved in the regulation of cell growth, differentiation, and metabolism. DDR2 plays a role in the regulation of collagen turnover mediated by smooth muscle cells in obstructive diseases of blood vessels and the lung (2).

7760 | DDR2 Active DataSheet

Biomolecule/Target: N/A

Synonyms: DDR, discoidin domain receptor tyrosine kinase 2

Alternates names: DDR, discoidin domain receptor tyrosine kinase 2, CD167 antigen-like family member B, Discoidin domain-containing receptor tyrosine kinase 2, Neurotrophic tyrosine kinase, receptor-related 3, Receptor protein-tyrosine kinase TKT, Tyrosine-protein kinase TYRO10

Taglines: Plays a key role in the communication of cells with their microenvironment

NCBI Gene ID #: UniGeneHs.419815

NCBI Gene Symbol: EGF

Gene Source: N/A

Accession #: Q6QBS2

Recombinant: Yes

Source: Baculovirus (Sf9 insect cells)

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: N/A

Activity (Specifications/test method): The specific activity of DDR2 was determined to be 25 nmol /min/mg as per activity assay protocol.

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 70.0 kDa

Concentration: 0.1mg/ml

Appearance: Liquid

Physical form description: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.

Reconstitution Instructions: N/A

Amino acid sequence: N/A