Description
DDR2 is a member of a novel subclass of RTKs containing a distinct extracellular region encompassing a factor VIII-like domain (1) and is thought to be involved in the regulation of cell growth, differentiation, and metabolism. DDR2 plays a role in the regulation of collagen turnover mediated by smooth muscle cells in obstructive diseases of blood vessels and the lung (2).
Biomolecule/Target: N/A
Synonyms: DDR, discoidin domain receptor tyrosine kinase 2
Alternates names: DDR, discoidin domain receptor tyrosine kinase 2, CD167 antigen-like family member B, Discoidin domain-containing receptor tyrosine kinase 2, Neurotrophic tyrosine kinase, receptor-related 3, Receptor protein-tyrosine kinase TKT, Tyrosine-protein kinase TYRO10
Taglines: Plays a key role in the communication of cells with their microenvironment
NCBI Gene ID #: UniGeneHs.419815
NCBI Gene Symbol: EGF
Gene Source: N/A
Accession #: Q6QBS2
Recombinant: Yes
Source: Baculovirus (Sf9 insect cells)
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: N/A
Assay #2: HPLC
Endotoxin Level: N/A
Activity (Specifications/test method): The specific activity of DDR2 was determined to be 25 nmol /min/mg as per activity assay protocol.
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 70.0 kDa
Concentration: 0.1mg/ml
Appearance: Liquid
Physical form description: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Reconstitution Instructions: N/A
Amino acid sequence: N/A