Description
An anticancer agent. Docetaxel binds to microtubules reversibly with high affinity and prevents microtubule depolymerization and disassembly in the absence of GTP. Used mainly for the treatment of breast, ovarian, and non-small cell lung cancer.
An anticancer agent and a microtubule depolymerization inhibitor.
Alternate Name/Synonyms: Taxotere; Docefrez
Appearance: White solid
Formulation: N/A
CAS Number: 114977-28-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₄₃H₅₃NO₁₄
Molecular Weight: 807.88
Cell-Permeable?: Yes
Purity: ≥99% by HPLC
Solubilities: DMSO (100 mM) or EtOH (100 mM)
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: An anticancer agent and a microtubule depolymerization inhibitor
MDL Number: MFCD00800737
PubChem CID: 148124
SMILES: CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O
InChi: InChI=1S/C43H53NO14/c1-22-26(55-37(51)32(48)30(24-15-11-9-12-16-24)44-38(52)58-39(3,4)5)20-43(53)35(56-36(50)25-17-13-10-14-18-25)33-41(8,34(49)31(47)29(22)40(43,6)7)27(46)19-28-42(33,21-54-28)57-23(2)45/h9-18,26-28,30-33,35,46-48,53H,19-21H2,1-8H3,(H,44,52)/t26-,27-,28+,30-,31+,32+,33-,35-,41+,42-,43+/m0/s1
InChi Key: ZDZOTLJHXYCWBA-VCVYQWHSSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24 months |
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