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Docetaxel | 2232

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SKU:
26-2232-GEN
Availability:
Usually shipped in 5 working days
£644.00 - £1,496.00

Description

An anticancer agent. Docetaxel binds to microtubules reversibly with high affinity and prevents microtubule depolymerization and disassembly in the absence of GTP. Used mainly for the treatment of breast, ovarian, and non-small cell lung cancer.

An anticancer agent and a microtubule depolymerization inhibitor.

2232 | Docetaxel DataSheet

Alternate Name/Synonyms: Taxotere; Docefrez

Appearance: White solid

Formulation: N/A

CAS Number: 114977-28-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₄₃H₅₃NO₁₄

Molecular Weight: 807.88

Cell-Permeable?: Yes

Purity: ≥99% by HPLC

Solubilities: DMSO (100 mM) or EtOH (100 mM)

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: An anticancer agent and a microtubule depolymerization inhibitor

MDL Number: MFCD00800737

PubChem CID: 148124

SMILES: CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O

InChi: InChI=1S/C43H53NO14/c1-22-26(55-37(51)32(48)30(24-15-11-9-12-16-24)44-38(52)58-39(3,4)5)20-43(53)35(56-36(50)25-17-13-10-14-18-25)33-41(8,34(49)31(47)29(22)40(43,6)7)27(46)19-28-42(33,21-54-28)57-23(2)45/h9-18,26-28,30-33,35,46-48,53H,19-21H2,1-8H3,(H,44,52)/t26-,27-,28+,30-,31+,32+,33-,35-,41+,42-,43+/m0/s1

InChi Key: ZDZOTLJHXYCWBA-VCVYQWHSSA-N

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Additional Information

Storage Condition:
-20°C
Shipping Condition:
Gel Pack
Shelf Life:
24 months
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