DR6 Antibody (Death Receptor 6)| F45509-0.08ML/F45509-0.4ML

DR6 Antibody (Death Receptor 6)| F45509-0.08ML/F45509-0.4ML | Gentaur UK, US & Europe Distribution

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: Mouse, Rat

Application: WB, ELISA

Application Details: Western blot: 1:1000

Application Note: Titration of the DR6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This DR6 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 356-385 from the human protein was used as the immunogen for this DR6 antibody.

Storage: Aliquot the DR6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A