EGF Receptor Antibody| F40405-0.08ML/F40405-0.4ML

EGF Receptor Antibody| F40405-0.08ML/F40405-0.4ML | Gentaur UK, US & Europe Distribution

Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Format: Purified

Clone: 688CT33.1.3

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Isotype: Mouse IgG1

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: WB, IHC, ELISA

Application Details: IHC (Paraffin): 1:25, Western blot: 1:1000

Application Note: Titration of the EGF Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This EGF Receptor antibody is available for research use only.

Purity: Purified

Immunogen: A portion of amino acids 1163-1191 from the human protein was used as the immunogen for this EGF Receptor antibody.

Storage: Aliquot the EGF Receptor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A