ERCC2 polyclonal Antibody | BS71942

ERCC2 polyclonal Antibody | BS71942 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Rat

Application: WB IF

Application Range: WB 1:500 - 1:2000 IF 1:50 - 1:100

Background: The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ERCC2 polyclonal Antibody detects endogenous levels of ERCC2 protein.

Molecular Weight: 87kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: COFS2; EM9; TFIIH; TTD; TTD1; XPD

Immunogen: Recombinant protein of human ERCC2

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: