BW
ERCC2 polyclonal Antibody | BS71942
- SKU:
- BW-BS71942
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- Usually ships in 5 working days
Description
ERCC2 polyclonal Antibody | BS71942 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Rat
Application: WB IF
Application Range: WB 1:500 - 1:2000 IF 1:50 - 1:100
Background: The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ERCC2 polyclonal Antibody detects endogenous levels of ERCC2 protein.
Molecular Weight: 87kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: COFS2; EM9; TFIIH; TTD; TTD1; XPD
Immunogen: Recombinant protein of human ERCC2
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: