Erk2 Antibody | 3442

Both p44 and p42 MAP kinases (Erk1 and Erk2) function in a protein kinase cascade that plays a critical role in the regulation of cell growth and differentiation. Activation of MAP kinases occurs thro?gh phosphorylation of threonine and tyrosine (202 and 204 of human MAP kinase [Erk1] or 183 and 185 of rat Erk2) at the sequence T*EY* by a single upstream MAP kinase kinase (MEK). Both kinases are known to weakly autophosphorylate on tyrosine.

3442 | Erk2 Antibody DataSheet

Antibody Target: Erk-2

Target Alternative Name: ERK , ERK-2 , MAPK2 , PRKM2, Extracellular signal-regulated kinase 2; ERK2; Defective in aggregation protein C; MAP kinase 2, Mitogen-activated protein kinase 1; MAP kinase 1; MAPK 1; Extracellular signal-regulated kinase 2; ERK-2; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2; MAP kinase isoform p42; p42-MAPK; ERT1.

Tag Line:

Category: Erk

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Human, mouse, rat

Immunogen Sequence: Synthetic peptide from human Erk2

Accession #: P28482.3

Gene ID: 119554

Appearance: Colorless liquid

Form: Liquid

Concentration: 0.5 mg/ml

Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal.

Purification: Affinity purified

Application: Western blot, Immunohistochemistry

Positive Control:

Application And Usages: Western blotting (0.5-4 µg/ml) and Immunohistochemistry (10-20 µg/ml). However, the optimal concentrations should be determined individually.

Country of Animal Origin: China

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: Verified

Immunocytochemistry Verified: Not Verified

Immunofluorescence Verified: Not Verified

Immunoprecipitation Verified: Not Verified

FACS Verified:

ELISA Verified: Not Verified

ChIP Verified: Not Verified

Dot Blot Verified:

Flow Cytometry Verified: Not Verified