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Estramustine phosphate sodium | B2652
- SKU:
- 26-B2652-GEN
- Availability:
- Usually shipped in 5 working days
Description
Estramustine phosphate sodium is a nitrogen mustard linked to estradiol that acts as a microtubule assembly inhibitor. Inhibits endothelial cell proliferation (IC₅₀ = 4.5 μM) and down-regulates prostate-specific antigen expression (IC₅₀ = 10.97 μM). Alkylating and antitumor agent.
Estramustine phosphate sodium is a nitrogen mustard linked to estradiol that acts as a microtubule assembly inhibitor. Inhibits endothelial cell proliferation (IC₅₀ = 4.5 μM) and down-regulates prostate-specific antigen expression (IC₅₀ = 10.97 μM). Alkylating and antitumor agent.
B2652 | Estramustine phosphate sodium DataSheet
Alternate Name/Synonyms: NSC 89201; Ro 22-2296/000; Estramustine sodium phosphate; Estramustine phosphate disodium; Estradiol 3-[N,N-Bis(2-chloroethyl)carbamate]; Estracyt
Appearance: Crystalline solid
Formulation:
CAS Number: 52205-73-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₃H₃₀Cl₂NNa₂O₆P
Molecular Weight: 564.3
Cell-Permeable?: True
Purity: ≥98%
Solubilities: 50 mg/ml in Water
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A microtubule assembly inhibitor
MDL Number: MFCD00866320
PubChem CID: 444000
SMILES: CC12CCC3C(C1CCC2OP(=O)([O-])[O-])CCC4=C3C=CC(=C4)OC(=O)N(CCCl)CCCl.[Na+].[Na+]
InChi: InChI=1S/C23H32Cl2NO6P.2Na/c1-23-9-8-18-17-5-3-16(31-22(27)26(12-10-24)13-11-25)14-15(17)2-4-19(18)20(23)6-7-21(23)32-33(28,29)30;;/h3,5,14,18-21H,2,4,6-13H2,1H3,(H2,28,29,30);;/q;2*+1/p-2/t18-,19-,20+,21+,23+;;/m1../s1
InChi Key: IIUMCNJTGSMNRO-VVSKJQCTSA-L
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |