Estramustine phosphate sodium | B2652

Estramustine phosphate sodium is a nitrogen mustard linked to estradiol that acts as a microtubule assembly inhibitor. Inhibits endothelial cell proliferation (IC₅₀ = 4.5 μM) and down-regulates prostate-specific antigen expression (IC₅₀ = 10.97 μM). Alkylating and antitumor agent.

Estramustine phosphate sodium is a nitrogen mustard linked to estradiol that acts as a microtubule assembly inhibitor. Inhibits endothelial cell proliferation (IC₅₀ = 4.5 μM) and down-regulates prostate-specific antigen expression (IC₅₀ = 10.97 μM). Alkylating and antitumor agent.

B2652 | Estramustine phosphate sodium DataSheet

Alternate Name/Synonyms: NSC 89201; Ro 22-2296/000; Estramustine sodium phosphate; Estramustine phosphate disodium; Estradiol 3-[N,N-Bis(2-chloroethyl)carbamate]; Estracyt

Appearance: Crystalline solid

Formulation:

CAS Number: 52205-73-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₃H₃₀Cl₂NNa₂O₆P

Molecular Weight: 564.3

Cell-Permeable?: True

Purity: ≥98%

Solubilities: 50 mg/ml in Water

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A microtubule assembly inhibitor

MDL Number: MFCD00866320

PubChem CID: 444000

SMILES: CC12CCC3C(C1CCC2OP(=O)([O-])[O-])CCC4=C3C=CC(=C4)OC(=O)N(CCCl)CCCl.[Na+].[Na+]

InChi: InChI=1S/C23H32Cl2NO6P.2Na/c1-23-9-8-18-17-5-3-16(31-22(27)26(12-10-24)13-11-25)14-15(17)2-4-19(18)20(23)6-7-21(23)32-33(28,29)30;;/h3,5,14,18-21H,2,4,6-13H2,1H3,(H2,28,29,30);;/q;2*+1/p-2/t18-,19-,20+,21+,23+;;/m1../s1

InChi Key: IIUMCNJTGSMNRO-VVSKJQCTSA-L