Fatostatin | 2035

Cell-permeable. Blocks adipogenesis by inhibiting the activation of SREBPs (Sterol Regulatory Binding Proteins). Inhibits the ER-Golgi translocation of SREBPs via binding to their escort protein (SCAP). Prevents increases in body weight, blood glucose and hepatic fat accumulation in obese ob/ob mice.

Fatostatin blocks adipogenesis by inhibiting the activation of SREBPs (Sterol Regulatory Binding Proteins). Inhibits the ER-Golgi translocation of SREBPs via binding to their escort protein (SCAP).

2035 | Fatostatin DataSheet

Alternate Name/Synonyms: 2-(2-propylpyridin-4-yl)-4-(p-tolyl)thiazole

Appearance: Yellow solid

Formulation: N/A

CAS Number: 298197-04-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₈H₁₈N₂S

Molecular Weight: 294.41

Cell-Permeable?: Yes

Purity: ≥98% by TLC

Solubilities: DMSO ( 25 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A Sterol Regulatory Binding Proteins (SREBPs) inhibitor

MDL Number: MFCD00760867

PubChem CID: 1889993

SMILES: CCCC1=NC=CC(=C1)C2=NC(=CS2)C3=CC=C(C=C3)C

InChi: InChI=1S/C18H18N2S/c1-3-4-16-11-15(9-10-19-16)18-20-17(12-21-18)14-7-5-13(2)6-8-14/h5-12H,3-4H2,1-2H3

InChi Key: ZROSUBKIGBSZCG-UHFFFAOYSA-N