Description
Formestane is a steroidal aromatase inhibitor. It binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens.
Formestane is a steroidal aromatase inhibitor. It binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens.
Alternate Name/Synonyms: (8R,9S,10R,13S,14S)-4-hydroxy-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17(2H,6H)-dione; CGP 32349; NSC 282175
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 566-48-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₉H₂₆O₃
Molecular Weight: 302.41
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (~10 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A steroidal aromatase inhibitor
MDL Number: MFCD00057814
PubChem CID: 11273
SMILES: CC12CCC(=O)C(=C1CCC3C2CCC4(C3CCC4=O)C)O
InChi: InChI=1S/C19H26O3/c1-18-10-8-15(20)17(22)14(18)4-3-11-12-5-6-16(21)19(12,2)9-7-13(11)18/h11-13,22H,3-10H2,1-2H3/t11-,12-,13-,18+,19-/m0/s1
InChi Key: OSVMTWJCGUFAOD-KZQROQTASA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |