Formestane | B2041

Formestane is a steroidal aromatase inhibitor. It binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens.

Formestane is a steroidal aromatase inhibitor. It binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens.

B2041 | Formestane DataSheet

Alternate Name/Synonyms: (8R,9S,10R,13S,14S)-4-hydroxy-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17(2H,6H)-dione; CGP 32349; NSC 282175

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 566-48-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₉H₂₆O₃

Molecular Weight: 302.41

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~10 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A steroidal aromatase inhibitor

MDL Number: MFCD00057814

PubChem CID: 11273

SMILES: CC12CCC(=O)C(=C1CCC3C2CCC4(C3CCC4=O)C)O

InChi: InChI=1S/C19H26O3/c1-18-10-8-15(20)17(22)14(18)4-3-11-12-5-6-16(21)19(12,2)9-7-13(11)18/h11-13,22H,3-10H2,1-2H3/t11-,12-,13-,18+,19-/m0/s1

InChi Key: OSVMTWJCGUFAOD-KZQROQTASA-N