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Fructose 1,6-bisphophatase 1, Active, Human Recombinant | P1269
- SKU:
- 26-P1269-GEN
- Availability:
- Usually shipped in 5 working days
Description
The conversion of fructose 1,6-bisphosphate to fructose 6 phosphate by fructose 1,6-bisphosphatase is the rate-limiting step during gluconeogenesis. The enzyme plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells and modulates glycerol gluconeogenesis in liver. It is involved in regulation of adiposity and appetite.
P1269 | Fructose 1 6-bisphophatase 1 Active Human Recombinant DataSheet
Biomolecule/Target: N/A
Synonyms: FBP1, Fructose 1,6-bisphophatase 1, FBP, FBPase 1, Liver FBPase, D-fructose-1,6-bisphosphate 1-phosphohydrolase 1
Alternates names: IgE-binding protein, MAC2, L-29, CPB-35, 35 kDa lectin, Carbohydrate-binding protein 35, Galactose-specific lectin 3, Galactoside-binding protein, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen
Taglines: A full length, active Fructose 1,6-bisphophatase 1 acting as the rate-limiting step during gluconeogenesis.
NCBI Gene ID #: 3958
NCBI Gene Symbol: LEG3
Gene Source: Human
Accession #: P17931
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: Determined by its ability to chemoattract human blood monocytes. Chemotactic activity was observed at a concentration of 2.5 µg/ml with a peak response obtained at 250 µg/ml.
Results: 1 U/mg
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 26.0 kDa
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: Lyophilized powder from 0.22 m filtered solution in PBS containing 8% trehalose
Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or 20°C for future use.
Amino acid sequence: N/A