Fructose 1,6-bisphophatase 1, Active, Human Recombinant | P1269

The conversion of fructose 1,6-bisphosphate to fructose 6 phosphate by fructose 1,6-bisphosphatase is the rate-limiting step during gluconeogenesis. The enzyme plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells and modulates glycerol gluconeogenesis in liver. It is involved in regulation of adiposity and appetite.

P1269 | Fructose 1 6-bisphophatase 1 Active Human Recombinant DataSheet

Biomolecule/Target: N/A

Synonyms: FBP1, Fructose 1,6-bisphophatase 1, FBP, FBPase 1, Liver FBPase, D-fructose-1,6-bisphosphate 1-phosphohydrolase 1

Alternates names: IgE-binding protein, MAC2, L-29, CPB-35, 35 kDa lectin, Carbohydrate-binding protein 35, Galactose-specific lectin 3, Galactoside-binding protein, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen

Taglines: A full length, active Fructose 1,6-bisphophatase 1 acting as the rate-limiting step during gluconeogenesis.

NCBI Gene ID #: 3958

NCBI Gene Symbol: LEG3

Gene Source: Human

Accession #: P17931

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: Determined by its ability to chemoattract human blood monocytes. Chemotactic activity was observed at a concentration of 2.5 µg/ml with a peak response obtained at 250 µg/ml.

Results: 1 U/mg

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 26.0 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Lyophilized powder from 0.22 m filtered solution in PBS containing 8% trehalose

Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

Amino acid sequence: N/A