GF-627368X | B2029

GW-627368X is a potent and selective competitive antagonist of the prostanoid EP4 receptor with additional affinity at TP receptors (pKi values are 7.0 and 6.8 in competition radioligand bioassays). Displays antitumor activity.

GW-627368X is a potent and selective competitive antagonist of the prostanoid EP4 receptor with additional affinity at TP receptors (pKi values are 7.0 and 6.8 in competition radioligand bioassays). Displays antitumor activity.

B2029 | GF-627368X DataSheet

Alternate Name/Synonyms: 4-(4-,9-Diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl)benzeneacetamide

Appearance: White solid

Formulation: N/A

CAS Number: 439288-66-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₀H₂₈N₂O₆S

Molecular Weight: 544.62

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>40 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent and selective competitive antagonist of the prostanoid EP4 receptor

MDL Number: N/A

PubChem CID: 5312130

SMILES: CCOC1=C2CN(C(=O)C2=C(C3=CC=CC=C31)OCC)C4=CC=C(C=C4)CC(=O)NS(=O)(=O)C5=CC=CC=C5

InChi: InChI=1S/C30H28N2O6S/c1-3-37-28-23-12-8-9-13-24(23)29(38-4-2)27-25(28)19-32(30(27)34)21-16-14-20(15-17-21)18-26(33)31-39(35,36)22-10-6-5-7-11-22/h5-17H,3-4,18-19H2,1-2H3,(H,31,33)

InChi Key: XREWXJVMYAXCJV-UHFFFAOYSA-N