Description
GW-627368X is a potent and selective competitive antagonist of the prostanoid EP4 receptor with additional affinity at TP receptors (pKi values are 7.0 and 6.8 in competition radioligand bioassays). Displays antitumor activity.
GW-627368X is a potent and selective competitive antagonist of the prostanoid EP4 receptor with additional affinity at TP receptors (pKi values are 7.0 and 6.8 in competition radioligand bioassays). Displays antitumor activity.
Alternate Name/Synonyms: 4-(4-,9-Diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl)benzeneacetamide
Appearance: White solid
Formulation: N/A
CAS Number: 439288-66-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₃₀H₂₈N₂O₆S
Molecular Weight: 544.62
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>40 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent and selective competitive antagonist of the prostanoid EP4 receptor
MDL Number: N/A
PubChem CID: 5312130
SMILES: CCOC1=C2CN(C(=O)C2=C(C3=CC=CC=C31)OCC)C4=CC=C(C=C4)CC(=O)NS(=O)(=O)C5=CC=CC=C5
InChi: InChI=1S/C30H28N2O6S/c1-3-37-28-23-12-8-9-13-24(23)29(38-4-2)27-25(28)19-32(30(27)34)21-16-14-20(15-17-21)18-26(33)31-39(35,36)22-10-6-5-7-11-22/h5-17H,3-4,18-19H2,1-2H3,(H,31,33)
InChi Key: XREWXJVMYAXCJV-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |