800
GPC3 Antibody| F44195-0.08ML/F44195-0.4ML
- SKU:
- 800-F44195-0.08ML/800-F44195-0.4ML
- Availability:
- Usually ships in 5 working days
Description
GPC3 Antibody| F44195-0.08ML/F44195-0.4ML | Gentaur UK, US & Europe Distribution
Background: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Isotype: Rabbit Ig
Species Reactivity: Human
Predicted Spacies Reactivity: N/A
Application: WB, ELISA
Application Details: Western blot: 1:1000
Application Note: Titration of the GPC3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Status: Available
Buffer: N/A
Limitation: This GPC3 antibody is available for research use only.
Purity: Antigen affinity
Immunogen: A portion of amino acids 465-494 from the human protein was used as the immunogen for this GPC3 antibody.
Storage: Aliquot the GPC3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Localization: N/A