Description
GV-58 is a Roscovitine (Cat. No. 1950) derivative that acts as a selective N- and P/Q-type Ca²⁺-channel agonist. These Ca2²⁺-channels regulate transmitter release in synapses. Potential lead compound for a variety of disorders that result in neuromuscular weakness.
GV-58 is a Roscovitine (Cat. No. 1950) derivative that acts as a selective N- and P/Q-type Ca²⁺-channel agonist. These Ca2²⁺-channels regulate transmitter release in synapses. Potential lead compound for a variety of disorders that result in neuromuscular weakness.
Alternate Name/Synonyms: (2R)-2-[(6-{[(5-Methylthiophen-2-yl)methyl]amino}-9-propyl-9H-purin-2-yl)amino]butan-1-ol; Rx-ID: 23159892
Appearance: White to off-white solid
Formulation: N/A
CAS Number: N/A
Structure Available?: Y
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₈H₂₆N₆OS
Molecular Weight: 374.5
Cell-Permeable?: Yes
Purity: >97% by NMR
Solubilities: DMSO or EtOH
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A calcium channel agonist
MDL Number: N/A
PubChem CID: N/A
SMILES: CC[C@@H](NC1=NC(NCC2=CC=C(C)S2)=C3N=CN(CCC)C3=N1)CO
InChi: InChI=1S/C18H26N6OS/c1-4-8-24-11-20-15-16(19-9-14-7-6-12(3)26-14)22-18(23-17(15)24)21-13(5-2)10-25/h6-7,11,13,25H,4-5,8-10H2,1-3H3,(H2,19,21,22,23)/t13-/m1/s1
InChi Key: DPTXJOUVBMUSGY-CYBMUJFWSA-N
Additional Information
Storage Condition: |
-20 ̊C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |