GV-58 | 2616

GV-58 is a Roscovitine (Cat. No. 1950) derivative that acts as a selective N- and P/Q-type Ca²⁺-channel agonist. These Ca2²⁺-channels regulate transmitter release in synapses. Potential lead compound for a variety of disorders that result in neuromuscular weakness.

GV-58 is a Roscovitine (Cat. No. 1950) derivative that acts as a selective N- and P/Q-type Ca²⁺-channel agonist. These Ca2²⁺-channels regulate transmitter release in synapses. Potential lead compound for a variety of disorders that result in neuromuscular weakness.

2616 | GV-58 DataSheet

Alternate Name/Synonyms: (2R)-2-[(6-{[(5-Methylthiophen-2-yl)methyl]amino}-9-propyl-9H-purin-2-yl)amino]butan-1-ol; Rx-ID: 23159892

Appearance: White to off-white solid

Formulation: N/A

CAS Number: N/A

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₈H₂₆N₆OS

Molecular Weight: 374.5

Cell-Permeable?: Yes

Purity: >97% by NMR

Solubilities: DMSO or EtOH

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A calcium channel agonist

MDL Number: N/A

PubChem CID: N/A

SMILES: CC[C@@H](NC1=NC(NCC2=CC=C(C)S2)=C3N=CN(CCC)C3=N1)CO

InChi: InChI=1S/C18H26N6OS/c1-4-8-24-11-20-15-16(19-9-14-7-6-12(3)26-14)22-18(23-17(15)24)21-13(5-2)10-25/h6-7,11,13,25H,4-5,8-10H2,1-3H3,(H2,19,21,22,23)/t13-/m1/s1

InChi Key: DPTXJOUVBMUSGY-CYBMUJFWSA-N