H-7 dihydrochloride | 9543

H-7 is a Protein kinase inhibitor that inhibits the activity of PKA, PKC, PKG and MLCK with IC₅₀ values of 3.0, 6.0, 5.8 and 97.0 µM, respectively.

H-7 is a Protein kinase inhibitor that inhibits the activity of PKA, PKC, PKG and MLCK with IC₅₀ values of 3.0, 6.0, 5.8 and 97.0 µM, respectively.

9543 | H-7 dihydrochloride DataSheet

Alternate Name/Synonyms: (±)-1-(5-Isoquinolinesulphonyl)-2-methylpiperazine dihydrochloride

Appearance: White solid

Formulation: N/A

CAS Number: 108930-17-2

Structure Available?: Yes

Peptide sequence: N

Salt Form: No

Molecular Formula: C₁₄H₁₇N₃O₂S.2HCl

Molecular Weight: 364.29

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>20 mg/ml) or H₂O (>20 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A protein kinase inhibitor

MDL Number: MFCD00036961

PubChem CID: 73332

SMILES: CC1CNCCN1S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl.Cl

InChi: InChI=1S/C14H17N3O2S.2ClH/c1-11-9-16-7-8-17(11)20(18,19)14-4-2-3-12-10-15-6-5-13(12)14;;/h2-6,10-11,16H,7-9H2,1H3;2*1H

InChi Key: OARGPFMFRLLKPF-UHFFFAOYSA-N