HMGB-1 Antibody| F45590-0.4ML

HMGB-1 Antibody| F45590-0.4ML | Gentaur UK, US & Europe Distribution

Background: DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity). [UniProt]

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: Mouse, Rat, Bovine, Pig, Primate, Hamster

Application: WB, ELISA

Application Details: Western blot: 1:1000

Application Note: Titration of the HMGB-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This HMGB-1 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 152-180 from the human protein was used as the immunogen for this HMGB-1 antibody.

Storage: Aliquot the HMGB-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A