HNF1B Antibody| F41209-0.08ML/F41209-0.4ML/R31391

HNF1B Antibody| F41209-0.08ML/F41209-0.4ML/R31391 | Gentaur UK, US & Europe Distribution

Background: This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: Mouse, Rat

Application: WB, ELISA

Application Details: Western blot: 1:1000

Application Note: Titration of the HNF1B antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This HNF1B antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 498-529 from the human protein was used as the immunogen for this HNF1B antibody.

Storage: Aliquot the HNF1B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A