Human CellExp™ BTN3A1 / CD277, Fc Tag, Human Recombinant | P1263

Butyrophilin subfamily 3 member A1 (BTN3A1) is also known as CD277 and BTF5, which belongs to the immunoglobulin superfamily and contains one B30.2/SPRY domain and two Ig-like V-type (immunoglobulin-like) domains. BTN3A1 plays a role in T-cell activation and in the adaptive immune response. Also, BTN3A1 regulates the proliferation of activated T-cells and the release of cytokines and IFNG by activated T-cells. Furthermore, BTN3A1 mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.

P1263 | Human CellExp BTN3A1 / CD277 Fc Tag Human Recombinant DataSheet

Biomolecule/Target: BTN3A1

Synonyms: BTN3A1, CD277, BTF5

Alternates names: Proepithelin, PEPI, PC Cell-derived Growth Factor.

Taglines: Plays a role in T-cell activation and in the adaptive immune response.

NCBI Gene ID #: 2896

NCBI Gene Symbol: GRN

Gene Source: Human

Accession #: P28799

Recombinant: Yes

Source: HEK293 cells

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per/g

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: ~74 kDa (observed due to glycosylation)

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 m filtered solution in 50 mM Tris, 100 mM Glycine, pH 7.5. Normally trehalose is added as protectant before lyophilization.

Reconstitution Instructions: N/A

Amino acid sequence: Signal peptide and human progranulin (aa 1-593) is untagged. Reflects the native sequence with no additional amino acids.