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Human CellExp™ CD200/OX-2, human recombinant | 7384
- SKU:
- 26-7384-GEN
- Availability:
- Usually shipped in 5 working days
Description
CD200 also known as OX-2 membrane glycoprotein (OX-2), is a type-1 membrane glycoprotein, which contains two immunoglobulin domains (1 Ig-like C2-type (immunoglobulin-like) domain and Ig-like V-type (immunoglobulin-like) domain), and thus belongs to the immunoglobulin superfamily. CD200 / OX-2 is widely expressed in multiple cell types. CD200 interacts with a structurally related receptor (CD200R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. OX-2 / CD200 and CD200R associate via their respective N-terminal Ig-like domains. CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.
7384 | Human CellExp CD200/OX-2 human recombinant DataSheet
Biomolecule/Target: CD200/OX-2
Synonyms: CD200, MOX1, MOX2, MRC, OX-2, My033
Alternates names: Trefoil Factor 2, Spasmolytic polypeptide (SP), Spasmolysin
Taglines: Involved in regulation of macrophage and mast cell function.
NCBI Gene ID #: 7032
NCBI Gene Symbol: TFF2
Gene Source: Human
Accession #: Q03404
Recombinant: Yes
Source: HEK293 cells
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: <1 EU/g by LAL method
Activity (Specifications/test method): N/A
Biological activity: Determined by its ability to chemoattract human monocytes using a concentration range of 1.0-10.0 µg/ml.
Results: 1.0-10.0 µg/ml
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 12.0 kDa
Concentration: N/A
Appearance: Lyophilized
Physical form description: Lyophilized from 0.22 m filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.
Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1-1.0 g/l. The solution can then be diluted into other aqueous buffers
Amino acid sequence: N/A