Human CellExp™ CD200/OX-2, human recombinant | 7384

CD200 also known as OX-2 membrane glycoprotein (OX-2), is a type-1 membrane glycoprotein, which contains two immunoglobulin domains (1 Ig-like C2-type (immunoglobulin-like) domain and Ig-like V-type (immunoglobulin-like) domain), and thus belongs to the immunoglobulin superfamily. CD200 / OX-2 is widely expressed in multiple cell types. CD200 interacts with a structurally related receptor (CD200R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. OX-2 / CD200 and CD200R associate via their respective N-terminal Ig-like domains. CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.

7384 | Human CellExp CD200/OX-2 human recombinant DataSheet

Biomolecule/Target: CD200/OX-2

Synonyms: CD200, MOX1, MOX2, MRC, OX-2, My033

Alternates names: Trefoil Factor 2, Spasmolytic polypeptide (SP), Spasmolysin

Taglines: Involved in regulation of macrophage and mast cell function.

NCBI Gene ID #: 7032

NCBI Gene Symbol: TFF2

Gene Source: Human

Accession #: Q03404

Recombinant: Yes

Source: HEK293 cells

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: <1 EU/g by LAL method

Activity (Specifications/test method): N/A

Biological activity: Determined by its ability to chemoattract human monocytes using a concentration range of 1.0-10.0 µg/ml.

Results: 1.0-10.0 µg/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 12.0 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 m filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.

Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1-1.0 g/l. The solution can then be diluted into other aqueous buffers

Amino acid sequence: N/A