IGF-BP1, human recombinant (new size) | 4717

Human IGF-BP1 is a 25.4 kDa cysteine-rich secreted protein expressed in liver, decidual, and kidneys and is the most abundant IGF-BP in amniotic fluid. Levels of IGF-BP1 in serum are lowest after food. IGF-BP1 binds both IGF-I and IGF-II with equal affinity. Phosphorylated IGF-BP1 hinders IGF actions, whereas nonphosphorylated IGF-BP1 is stimulatory. Recombinant human IGF-BP1 is a single, glycosylated protein consisting of 218 amino acid residues.

4717 | IGF-BP1 human recombinant new size DataSheet

Biomolecule/Target: N/A

Synonyms: IBP-1, IGF-Binding Protein 1, AFBP, PP12, IGF-BP25, hIGFBP-1, IGFBP-1.

Alternates names: IBP-1, IGF-Binding Protein 1, AFBP, PP12, IGF-BP25, hIGFBP-1, IGFBP-1.

Taglines: A protein which binds and prolongs the half-life of the IGFs

NCBI Gene ID #: 77125

NCBI Gene Symbol: IL33

Gene Source: Human

Accession #: Q8BVZ5

Recombinant: Yes

Source: Nso cells

Purity by SDS-PAGEs: 97%

Assay: SDS-PAGE

Purity: 98%

Assay #2: HPLC

Endotoxin Level: <0.1 ng/g

Activity (Specifications/test method): N/A

Biological activity: The ED as determined by the dose-dependent stimulation of the proliferation of murine D10S cells is 0.5 ng/ml, corresponding to a specific activity of 2 x 10 units/mg.

Results: ~100 ng/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 28.8 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Sterile filtered and lyophilized from 10 mM HCl.

Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and store at 4°C for 1 week or –20°C for future use.

Amino acid sequence: N/A