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IGF-BP1, human recombinant (new size) | 4717
- SKU:
- 26-4717-GEN
- Availability:
- Usually shipped in 5 working days
Description
Human IGF-BP1 is a 25.4 kDa cysteine-rich secreted protein expressed in liver, decidual, and kidneys and is the most abundant IGF-BP in amniotic fluid. Levels of IGF-BP1 in serum are lowest after food. IGF-BP1 binds both IGF-I and IGF-II with equal affinity. Phosphorylated IGF-BP1 hinders IGF actions, whereas nonphosphorylated IGF-BP1 is stimulatory. Recombinant human IGF-BP1 is a single, glycosylated protein consisting of 218 amino acid residues.
4717 | IGF-BP1 human recombinant new size DataSheet
Biomolecule/Target: N/A
Synonyms: IBP-1, IGF-Binding Protein 1, AFBP, PP12, IGF-BP25, hIGFBP-1, IGFBP-1.
Alternates names: IBP-1, IGF-Binding Protein 1, AFBP, PP12, IGF-BP25, hIGFBP-1, IGFBP-1.
Taglines: A protein which binds and prolongs the half-life of the IGFs
NCBI Gene ID #: 77125
NCBI Gene Symbol: IL33
Gene Source: Human
Accession #: Q8BVZ5
Recombinant: Yes
Source: Nso cells
Purity by SDS-PAGEs: 97%
Assay: SDS-PAGE
Purity: 98%
Assay #2: HPLC
Endotoxin Level: <0.1 ng/g
Activity (Specifications/test method): N/A
Biological activity: The ED as determined by the dose-dependent stimulation of the proliferation of murine D10S cells is 0.5 ng/ml, corresponding to a specific activity of 2 x 10 units/mg.
Results: ~100 ng/ml
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 28.8 kDa
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: Sterile filtered and lyophilized from 10 mM HCl.
Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and store at 4°C for 1 week or 20°C for future use.
Amino acid sequence: N/A