Description
IL-17A Antibody [17-142F] | 36-072 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: Recombinant human IL-17A.
Research Area: Innate Immunity
Tested Application: E, Flow
Application: ELISA: (direct and indirect: 1:500-1:5, 000) . Flow Cytometry: (1:20-1:500) . Optimal conditions must be determined individually for each application.
Specificiy: Recognizes human IL-17A.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: 17-142F
Isotype: IgG1, kappa
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration: 0.5 mg/ml
Storage Condition: Stable for at least 1 year after receipt when stored at -20˚C.
Alternate Name: Interleukin-17A; CTLA-8; Cytotoxic T Lymphocyte-associated Antigen 8
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: IL-17A exhibits multiple biological activities on a variety of cells including the induction of IL-6 and IL-8 production in fibroblsts, the enhancement of surface expression of ICAM-1 in fibroblast, activation of NF-kappaB and costimulation of T cell proliferation. Induces stromal cells to produce proinflammatory and hematopoietic cytokines.