IMPAD1, human recombinant | 7812

IMPAD1, also known as Inositol monophosphatase 3, is a member of the inositol monophosphatase family. IMPAD1 is localized to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). Mutations in this gene are a cause of GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of this gene is located on the long arm of chromosome 1. Recombinant human IMPAD1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

7812 | IMPAD1 human recombinant DataSheet

Biomolecule/Target: IMPAD1

Synonyms: Inositol monophosphatase 3, GPAPP, IMP 3, IMP-3, IMPA3

Alternates names: Inositol monophosphatase 3, GPAPP, IMP 3, IMP-3, IMPA3

Taglines: Catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP).

NCBI Gene ID #: 10631

NCBI Gene Symbol: POSTN

Gene Source: Human

Accession #: Q15063

Recombinant: Yes

Source: E. coli.

Purity by SDS-PAGEs: 90%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: Specific activity > 3300 pmole/min/µg

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 37.6 kDa (349 aa, 34-359 aa + His Tag)

Concentration: 0.25 mg/ml

Appearance: Liquid

Physical form description: 0.25 mg/ml solution in PBS (pH 7.4).

Reconstitution Instructions: N/A

Amino acid sequence: MGSSHHHHHH SSGLVPRGSH MGSGRFSLFG LGGEPGGGAA GPAAAADGGT VDLREMLAVS VLAAVRGGDE VRRVRESNVL HEKSKGKTRE GAEDKMTSGD VLSNRKMFYL LKTAFPSVQI NTEEHVDAAD QEVILWDHKI PEDILKEVTT PKEVPAESVT VWIDPLDATQ EYTEDLRKYV TTMVCVAVNG KPMLGVIHKP FSEYTAWAMV DGGSNVKARS SYNEKTPRIV VSRSHSGMVK QVALQTFGNQ TTIIPAGGAG YKVLALLDVP DKSQEKADLY IHVTYIKKWD ICAGNAILKA LGGHMTTLSG EEISYTGSDG IEGGLLASIR MNHQALVRKL PDLEKTGHK