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IMPAD1, human recombinant | 7812
- SKU:
- 26-7812-GEN
- Availability:
- Usually shipped in 5 working days
Description
IMPAD1, also known as Inositol monophosphatase 3, is a member of the inositol monophosphatase family. IMPAD1 is localized to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). Mutations in this gene are a cause of GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of this gene is located on the long arm of chromosome 1. Recombinant human IMPAD1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
7812 | IMPAD1 human recombinant DataSheet
Biomolecule/Target: IMPAD1
Synonyms: Inositol monophosphatase 3, GPAPP, IMP 3, IMP-3, IMPA3
Alternates names: Inositol monophosphatase 3, GPAPP, IMP 3, IMP-3, IMPA3
Taglines: Catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP).
NCBI Gene ID #: 10631
NCBI Gene Symbol: POSTN
Gene Source: Human
Accession #: Q15063
Recombinant: Yes
Source: E. coli.
Purity by SDS-PAGEs: 90%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: Specific activity > 3300 pmole/min/µg
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 37.6 kDa (349 aa, 34-359 aa + His Tag)
Concentration: 0.25 mg/ml
Appearance: Liquid
Physical form description: 0.25 mg/ml solution in PBS (pH 7.4).
Reconstitution Instructions: N/A
Amino acid sequence: MGSSHHHHHH SSGLVPRGSH MGSGRFSLFG LGGEPGGGAA GPAAAADGGT VDLREMLAVS VLAAVRGGDE VRRVRESNVL HEKSKGKTRE GAEDKMTSGD VLSNRKMFYL LKTAFPSVQI NTEEHVDAAD QEVILWDHKI PEDILKEVTT PKEVPAESVT VWIDPLDATQ EYTEDLRKYV TTMVCVAVNG KPMLGVIHKP FSEYTAWAMV DGGSNVKARS SYNEKTPRIV VSRSHSGMVK QVALQTFGNQ TTIIPAGGAG YKVLALLDVP DKSQEKADLY IHVTYIKKWD ICAGNAILKA LGGHMTTLSG EEISYTGSDG IEGGLLASIR MNHQALVRKL PDLEKTGHK