Imperatorin | 2318

A furanocoumarin isolated from Opopanax chironium L. Displays anticancer properties. It induces apoptosis as well as DNA fragmentation at the G1/S phase of the cell cycle. Imperatorin sensitizes anoikis and inhibits anchorage-independent growth of lung cancer cells. Modulator of SMAD1/5/8, p38, ERK pathways. Also acts as a L-type calcium channel blocker.

Imperatorin displays anticancer properties and induces apoptosis as well as DNA fragmentation at the G1/S phase of the cell cycle. Imperatorin also sensitizes anoikis and inhibits anchorage-independent growth of lung cancer cells

2318 | Imperatorin DataSheet

Alternate Name/Synonyms: 9-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one; Pentosalen; Marmelosin; Ammidin; NSC 402949; BAN

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 482-44-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₆H₁₄O₄

Molecular Weight: 270.28

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: An anticancer agent

MDL Number: MFCD00016881

PubChem CID: 10212

SMILES: CC(=CCOC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2)C

InChi: InChI=1S/C16H14O4/c1-10(2)5-7-19-16-14-12(6-8-18-14)9-11-3-4-13(17)20-15(11)16/h3-6,8-9H,7H2,1-2H3

InChi Key: OLOOJGVNMBJLLR-UHFFFAOYSA-N