Description
Indisulam is a novel sulfonamide antitumor agent that displays potent antitumor activity in vitro and in vivo. It affects cell cycle progression in human tumor cells. Indisulam also acts as a carbonic anhydrase inhibitor.
Indisulam is a novel sulfonamide antitumor agent that displays potent antitumor activity in vitro and in vivo. It affects cell cycle progression in human tumor cells. Indisulam also acts as a carbonic anhydrase inhibitor.
Alternate Name/Synonyms: E7070 ER-35744 D04522 ER35744 N-(3-Chloro-1H-indol-7-yl)-1,4-benzenedisulfonamide
Appearance: Grey to pinkish solid
Formulation:
CAS Number: 165668-41-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₄H₁₂ClN₃O₄S₂
Molecular Weight: 385.85
Cell-Permeable?: True
Purity: ≥98% by HPLC
Solubilities: ~20 mg/ml in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A carbonic anhydrase inhbitor
MDL Number: MFCD00945325
PubChem CID: 216468
SMILES: C1=CC2=C(C(=C1)NS(=O)(=O)C3=CC=C(C=C3)S(=O)(=O)N)NC=C2Cl
InChi: InChI=1S/C14H12ClN3O4S2/c15-12-8-17-14-11(12)2-1-3-13(14)18-24(21,22)10-6-4-9(5-7-10)23(16,19)20/h1-8,17-18H,(H2,16,19,20)
InChi Key: SETFNECMODOHTO-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |