Integrin beta 2 Antibody| F40395-0.4ML

Integrin beta 2 Antibody| F40395-0.4ML | Gentaur UK, US & Europe Distribution

Background: The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.

Format: Purified

Clone: 534CT6.2.1

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Isotype: Mouse IgG1

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: IHC, WB, ELISA

Application Details: IHC (Paraffin): 1:25, Western blot: 1:100-1:1000

Application Note: Titration of the Integrin beta 2antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This Integrin beta 2antibody is available for research use only.

Purity: Purified

Immunogen: Purified His-tagged protein fragment was used to produced this monoclonal Integrin beta 2 antibody.

Storage: Aliquot the Integrin beta 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A