800
Integrin beta 2 Antibody (ITGB2)| F40395-0.08ML
- SKU:
- 800-F40395-0.08ML
- Availability:
- Usually ships in 5 working days
Description
Integrin beta 2 Antibody (ITGB2)| F40395-0.08ML | Gentaur UK, US & Europe Distribution
Background: The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.
Format: Purified
Clone: 534CT6.2.1
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Isotype: Mouse IgG1
Species Reactivity: Human
Predicted Spacies Reactivity: N/A
Application: IHC, WB, ELISA
Application Details: IHC (Paraffin): 1:25, Western blot: 1:100-1:1000
Application Note: Titration of the Integrin beta 2antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Status: Available
Buffer: N/A
Limitation: This Integrin beta 2antibody is available for research use only.
Purity: Purified
Immunogen: Purified His-tagged protein fragment was used to produced this monoclonal Integrin beta 2 antibody.
Storage: Aliquot the Integrin beta 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Localization: N/A