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Isopeptidase T (long form), human recombinant | 4862
- SKU:
- 26-4862-GEN
- Availability:
- Usually shipped in 5 working days
Description
Isopeptidase T is a ubiquitin-specific processing protease (UBP) that specifically disassembles free K48-linked polyubiquitin chains into ubiquitin monomers. There are two human isopeptidase T isoforms; Isopeptidase T short form (isoT-S) and Isopeptidase T long form (isoT-L) which differ by an insertion of 23 amino acids in isoT-L. Isopeptidase T is the only UBP known to require zinc binding to be active.
4862 | Isopeptidase T long form human recombinant DataSheet
Biomolecule/Target: N/A
Synonyms: USP5; Ubiquitin-specific protease 5
Alternates names: USP5; Ubiquitin-specific protease 5
Taglines: A ubiquitin-specific processing protease
NCBI Gene ID #: 20296
NCBI Gene Symbol: MCP-1
Gene Source: Human
Accession #: P10148
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: N/A
Assay #2: HPLC
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: Determined by measuring the dose dependent chemotaxis with human THP-1 cells. The ED is in the range of 1-10 ng/ml.
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 97.0 kDa
Concentration: 0.4 mg/ml
Appearance: Liquid
Physical form description: Supplied at a concentration of 0.4 mg/ml in 50 mM Tris, 10 Mmn -mercaptoethanol, pH 7.5.
Reconstitution Instructions:
Amino acid sequence: